Welcome to the Basta lab!
Currently, her lab studies mycobacterial LD-transpeptidase enzymes toward opportunities for antimicrobial development. She has trained a number of midshipmen with interests in biochemistry and medicine, and many of her students have gone on to study at prestigious medical schools.
Zandi TA, Marshburn RL, Stateler PK, Brammer Basta LA
ACS Infect. Dis., vol. 5(12), 2019, pp. 2047-2054
Bianchet MA, Pan YH, Brammer Basta LA, Saavedra H, Lloyd EP, Kumar P, Mattoo R, Townsend CA, Lamichhane G
BMC Biochem., vol. 18(1), 2017, p. 1
Brammer Basta LA, Ghosh A, Pan Y, Jakoncic J, Lloyd EP, Townsend CA, Lamichhane G, Bianchet MA.
J. Biol. Chem., vol. 290(42), 2015, pp. 25670-25685
Brammer Basta LA, Patel H, Kakalis L, Jordan F, Freel Meyers CL
FEBS J, vol. 281(12), 2014, pp. 2820-2837
Observation of thiamin-bound intermediates and microscopic rate constants for their interconversion on 1-deoxy-D-xylulose 5-phosphate synthase: 600-fold rate acceleration of pyruvate decarboxylation by D-glyceraldehyde-3-phosphate.
Patel H, Nemeria NS, Brammer LA, Freel Meyers CL, Jordan F
J. Am. Chem. Soc., vol. 134(44), 2012, pp. 18374-18379
The first in a two-semester sequence presenting the fundamental laws and theories of chemistry. Naval applications of chemistry are introduced throughout the courses to provide an awareness of chemistry in normal Navy operations.
This is the second in the two-course foundations of chemistry sequence. See SC111 for a general course description. Naval applications including corrosion, nuclear power, boiler water quality, aircraft deicing, and scuba diving will be emphasized.
The chemical basis of life will be examined by studying the relationship between the structure and the function of biological macromolecules. There will be an overview of modern biochemical experimental methods.
Two-semester research course where students will work 6 hours a week in lab with Prof. Basta. Research in Prof. Basta's lab fulfills the Biochemistry concentration research requirement.
Intro to fundamental principles of biology are introduced, including metabolism, cell structure & function, classical & molecular genetics, & evolution.